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產(chǎn)品名稱: |
鈣結(jié)合蛋白Calponin (Basic)抗體 |
產(chǎn)品型號: |
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產(chǎn)品產(chǎn)地: |
中國大陸 |
訪問次數(shù): |
1508 |
發(fā)布時間: |
2016/3/29 15:37:15 |
Calponin (Basic) is an actin, tropomyosin and calmodulin binding protein thought to be involved in the regulation of smooth muscle contraction. |
鈣結(jié)合蛋白Calponin (Basic)抗體 Clone 26A11 7 mL BOND ready-to-use PA0416 P (HIER) Antigen Background Calponin (Basic) is an actin, tropomyosin and calmodulin binding protein thought to be involved in the regulation of smooth muscle contraction. The expression of basic calponin is reported to be restricted to smooth muscle cells and is a marker of the differentiated contractile phenotype of developing smooth muscle. Vascular smooth muscle cells convert to a synthetic dedifferentiated phenotype when this protein is lost and this is a key stage in both atherosclerosis and restenosis of coronary arteries after balloon angioplasty. It is thought that basic calponin exerts its effect via the cortical actin cytoskeleton and therefore influences proliferation, the transformed phenotype and the metastatic potential of tumor cells. Basic calponin mRNA is expressed in smooth muscle of prostate, bowel and aorta whereas neutral and acidic calponin mRNAs are expressed in non-smooth muscle tissues such as heart, placenta, lung, kidney, pancreas, spleen, testis and ovary as well as in smooth muscle-containing tissues.
Breast carcinoma: immunohistochemical staining with BOND ready-to-use Calponin (Basic) (26A11) using BOND Polymer Refine Detection.
更新時間:2024/11/12 13:40:42
經(jīng)營許可證號:滬寶食藥監(jiān)械經(jīng)營許20220040號
標簽:鈣結(jié)合蛋白抗體 Calponin Clone 26A11
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